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KMID : 0358420170600050477
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Korean Journal of Obstetrics and Gynecology
2017 Volume.60 No. 5 p.477 ~ p.480
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BRCA1-mutated ovarian cancer with skin metastasis: a case report
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Oh So-Ra
Park Jung-Woo
Kwon Hyun-Young
Rha Seo-Hee
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Abstract
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The major risk factor for ovarian cancer (OC) is mutation of the BRCA1 or BRCA2 DNA mismatch repair genes, which occurs in approximately 10% of OC cases. Most previous studies have demonstrated that BRCA1- and BRCA2-mutated OCs are associated with better prognosis than sporadic OCs. However, information about the patterns and clinical course of the metastatic spread of BRCA-mutated OCs is limited. Herein, we describe a case of OC with a BRCA1 mutation and skin metastases in a 49-year-old patient, which to the best of our knowledge has not been reported previously.
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KEYWORD
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Skin metastases, Ovarian neoplasms, BRCA mutation
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